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Longevity & Cellular Research

Mitochondrial, thymic and bioregulator signalling compounds.

Longevity and cellular research compounds span mitochondrial-derived peptides, mitochondria-targeted antioxidant sequences, short bioregulators and senolytic constructs. What unites them is the compartment they are studied in, not a shared mechanism.

These compounds are supplied for laboratory research only. No anti-ageing, life-extension or therapeutic claim is made or implied, and none of this material may be administered to humans or animals.

Longevity & Cellular Research research compounds

Mitochondrial-derived and mitochondria-targeted peptides

MOTS-c is a mitochondrial-derived peptide encoded within the mitochondrial genome rather than nuclear DNA, and is studied in metabolic-homeostasis and AMPK-pathway models. SS-31 (elamipretide) is a different proposition — a synthetic tetrapeptide designed to concentrate at the inner mitochondrial membrane through cardiolipin association, studied in bioenergetic and oxidative-stress work.

Because these compounds are studied at the organelle level, assay design usually involves mitochondrial isolation or live-cell respirometry rather than simple receptor binding. Carryover of diluent components into respirometry buffers is a frequent confounder.

Bioregulator peptides

Epitalon, pinealon and related bioregulators are very short sequences — often two to four residues — originating from Russian peptide bioregulator research. Their brevity has practical consequences: they are highly soluble, they elute very early on reverse-phase columns, and standard C18 methods developed for longer sequences may not retain them adequately.

Short sequences also give small, less distinctive mass spectra. Identity confirmation benefits from high resolution MS rather than nominal-mass instruments.

Cofactors and senolytic constructs

NAD+ is a nucleotide cofactor rather than a peptide, supplied for sirtuin and cellular-metabolism research. It is notably hygroscopic and degrades in solution faster than most peptides in this catalog, so it is reconstituted immediately before use.

FOXO4-DRI is a retro-inverso D-amino-acid peptide studied in senescent-cell models. The retro-inverso construction confers resistance to proteolysis, which also means it behaves differently from the L-form sequence in any degradation assay.

Longevity & Cellular Research — frequently asked questions

Related research categories

All compounds listed on this page are supplied for laboratory research use only. They are not drugs, supplements or cosmetics, and are not intended for human or veterinary consumption. See our research use policy.