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Semaglutide 2 mg lyophilized research peptide vial, PRIMEGEN LABS front label. Buy Semaglutide 2 mg from PrimeGen Labs — 99.3% purity lyophilized Semaglutide peptide for laboratory research, third party tested by HPLC and mass spectrometry, supplied in a sealed 10 mL borosilicate vial with a batch-matched certificate of analysis.

Best sellerWeight Management Research

Semaglutide

GLP-1 receptor agonist

In stock

Select strength

Long-acting GLP-1 analog widely referenced in incretin signalling and metabolic research models.

$23.00
  • Third-party tested
  • Ambient-stable transit
  • Lot traceable
  • Batch-matched COA
  • Tracked delivery
  • Research use only

For laboratory research use only. Not for human or veterinary consumption.

Laboratory specifications

Purity (RP-HPLC)
99.3%
Molecular formula
C187H291N45O59
Molecular weight
4113.58 g/mol
CAS number
910463-68-2
Form
Lyophilized powder
Appearance
White to off-white lyophilized powder or cake, free of visible particulates.
Solubility
Sterile or bacteriostatic water; DMSO for hydrophobic sequences
Endotoxin
< 0.25 EU/mg
Fill weight
2 mg
Storage temperature
-20 °C sealed · 2–8 °C after reconstitution
Shelf life
36 months at -20 °C from the manufacture date
Reconstitution
Add diluent slowly down the vial wall; do not shake or vortex
Synthesis
Solid-phase (SPPS)
Identity
ESI-MS confirmed
Residual solvent
< 0.5%
Closure
Crimped aluminium / butyl stopper
Manufacturer
PRIMEGEN LABS · PrimeGen Co.

Storage & handling

  • Long-term

    -20 °C, sealed, desiccated

  • In transit

    Ambient stable up to 21 days

  • After reconstitution

    2–8 °C, use within 21 days

  • Light exposure

    Protect from direct light

Certificate of analysis

Lot XX · HPLC + MS report issued by an independent laboratory. The released PDF is available on request.

Lot number
XX
EXP
XX/XXXX
COA date
On request
Testing laboratory
Independent ISO lab
Purity
99.3%
Testing method
RP-HPLC + ESI-MS
Batch status
Released — report on request
A batch-matched digital certificate for lot XX is available on request.

Research background

Semaglutide is a synthetic analog of human glucagon-like peptide-1 in which two residue substitutions and a C-18 diacid side chain markedly slow enzymatic clearance. It became a reference incretin analog in metabolic literature because its extended plasma residence allows week-scale pharmacodynamic modelling that native GLP-1, with a half-life measured in minutes, cannot support.

Mechanism of action

Published work describes selective agonism at the GLP-1 receptor, a class B G-protein-coupled receptor. Receptor occupancy elevates intracellular cAMP and activates protein kinase A, which in pancreatic beta-cell models is associated with glucose-dependent insulin secretion. The albumin-binding fatty-acid moiety and the Aib substitution at position 8 reduce dipeptidyl peptidase-4 cleavage, which is the principal reason for the extended observed half-life.

Areas of scientific investigation

  • Incretin receptor pharmacology and cAMP signalling assays
  • Energy-balance and food-intake models in rodents
  • Beta-cell culture and insulin secretion studies
  • Comparative agonist potency screening against GIP and glucagon receptors

Listed fields describe where this sequence appears in published in vitro and preclinical literature. They are not indications, applications, or claims of effect.

Laboratory handling

Reconstitution

Dissolves readily in sterile or bacteriostatic water. Because of the lipid side chain, add diluent slowly down the vial wall and allow several minutes of quiescent dissolution rather than agitating; foaming indicates shear and should be avoided.

Stability

Reconstituted solutions are typically handled at 2-8 °C and protected from light. Repeated freeze-thaw cycling of aqueous stock is not recommended in the literature because of aggregation at the lipidated terminus.

Packaging

Single sequence per vial, sealed under inert gas in USP Type I borosilicate glass with a butyl rubber stopper and crimped aluminium overseal. Each vial carries a printed PRIMEGEN LABS label with product name, strength, lot number, manufacture and retest dates, storage temperature and a QR code linking to the lot record. Vials ship in a rigid foam insert inside a protective mailer at ambient temperature.

Frequently asked questions

Compare with similar compounds

Semaglutide vs Tirzepatide, Retatrutide, Cagrilintide

Open full comparison
Semaglutide compared with similar research compounds
CompoundStrengthCategoryMolecular weightAvailabilityPrice
SemaglutideThis page2 mgWeight Management Research4113.58 g/molIn stock$23.00
Tirzepatide5 mgWeight Management Research4813.45 g/molIn stock$45.00
Retatrutide5 mgWeight Management Research~4731 g/molBackorder · next lot, 5–7 business days$60.00
Cagrilintide5 mgWeight Management Research~3750 g/molIn stock$85.00

Complete your order

Laboratory consumables matched to 1 vial in your cart.

  • Bacteriostatic Water — 30 mL

    Bacteriostatic Water

    30 mL

    1 × 30 mL — one vial of diluent per 3 peptide vials

    $16.00
  • Sterile Syringes — 10-pack · 1 mL

    Sterile Syringes

    10-pack · 1 mL

    10-pack covers a standard order

    $13.00
  • Alcohol Prep Pads — 100-pack

    Alcohol Prep Pads

    100-pack

    Septum decontamination before every draw

    $9.00
  • Vial Storage Case — 25 slots

    Vial Storage Case

    25 slots

    Keeps lots organised and light-protected

    $33.00

Research stacks

Stacks that include SEMAGLUTIDE

  • Weight Management Stack

    Semaglutide 5 mg · AOD-9604 5 mg · MOTS-c 10 mg

    View stack

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