Back to all compounds

Swipe to change view · pinch to zoom

Tesamorelin 20 mg lyophilized research peptide vial, PRIMEGEN LABS front label. Buy Tesamorelin 20 mg from PrimeGen Labs — 99.0% purity lyophilized Tesamorelin peptide for laboratory research, third party tested by HPLC and mass spectrometry, supplied in a sealed 10 mL borosilicate vial with a batch-matched certificate of analysis.

Growth Hormone Research

Tesamorelin

Stabilized GHRH analog

Trans-3-hexenoyl GHRH analog referenced in visceral adipose-tissue research.

In stock

Quantity

1

Price

$132.00

Shipping & delivery

  • United States onlyDispatched from our US facility in Chase City, Virginia.
  • 10–12 business daysLyophilized material is ambient-stable in protective, discreet packaging.
  • Tracking after dispatchA tracking number is emailed once your order ships.

Shipping costs are calculated at checkout. Full shipping information · Refund & damage policy

At a glance

  • Third-Party Tested
  • Lot-matched documentation
  • HPLC purity data (99.293%)
  • Ambient-Stable Transit
  • Lot Traceable
  • Tracked Delivery
  • Research Use Only
  • Ships from United States

Key facts

Tesamorelin 20 mg is a lyophilized research peptide supplied by PrimeGen Co. (vial branded PRIMEGEN LABS) for laboratory research use only. Trans-3-hexenoyl GHRH analog referenced in visceral adipose-tissue research. Each lot is RP-HPLC assayed at 99.293% purity with a lot-matched certificate of analysis available digitally. It is not a drug, supplement, or cosmetic and is not for human or veterinary use.

Compound:
Tesamorelin 20 mg
Strength:
20 mg
Purity (RP-HPLC):
99.293%
Form:
Lyophilized powder, sealed vial
Verification:
Third-party HPLC & MS
Price:
$132.00 USD
Storage:
-20 °C sealed · 2–8 °C after reconstitution
Ships from:
United States
Shipping:
United States only · 10–12 business days
Certificate of analysis:
Lot-matched COA available
Intended use:
Laboratory research use only
Stock status:
In stock

Tesamorelin is catalogued under Research Peptides and Weight Management Research. Each lot ships with third-party certificate of analysis documentation, is released against our quality control process, and is dispatched from southern Virginia — see shipping information and the FAQ before ordering.

For laboratory research use only. Not for human or veterinary consumption.

Laboratory specifications

Purity (RP-HPLC)
99.293%
Molecular formula
C221H366N72O67S
Molecular weight
5135.9 g/mol
CAS number
218949-48-5
Form
Lyophilized powder
Appearance
White to off-white lyophilized powder or cake, free of visible particulates.
Solubility
Sterile or bacteriostatic water; DMSO for hydrophobic sequences
Endotoxin
< 0.25 EU/mg
Fill weight
20 mg
Storage temperature
-20 °C sealed · 2–8 °C after reconstitution
Shelf life
36 months at -20 °C from the manufacture date
Reconstitution
Add diluent slowly down the vial wall; do not shake or vortex
Synthesis
Solid-phase (SPPS)
Identity
ESI-MS confirmed
Residual solvent
< 0.5%
Closure
Crimped aluminium / butyl stopper
Distributed by
PrimeGen Co.

Storage & handling

  • Long-term

    -20 °C, sealed, desiccated

  • In transit

    Ambient stable up to 21 days

  • After reconstitution

    2–8 °C, use within 21 days

  • Light exposure

    Protect from direct light

Certificate of analysis

Janoshik Analytical report #109945 · sample submitted as Tesamorelin 5 mg.

Lot number
XX
EXP
XX/XXXX
COA date
19 Feb 2026
Testing laboratory
Janoshik Analytical
Purity
99.293%
Testing method
RP-HPLC + ESI-MS
Batch status
Released
Measured content
5.37 mg
Verification key
W2R12KWH1839
Page one of the Janoshik Analytical certificate of analysis for Tesamorelin 20 mg, report #109945, showing 99.293% purity
Janoshik Analytical report #109945 · analyzed 19 Feb 2026 · 99.293% purity. Tap to open the full PDF.

Scientific overview

Research summary: Trans-3-hexenoyl GHRH analog referenced in visceral adipose-tissue research.

Tesamorelin is a GHRH(1-44) analog bearing a trans-3-hexenoyl group on the N-terminal tyrosine. The acylation is the defining structural feature and the reason it appears in literature concerned with protease-resistant GHRH scaffolds.

Mechanism of action

Binds and activates the GHRH receptor with potency comparable to native hormone. The hexenoyl modification blocks N-terminal DPP-4 attack, extending in vitro and in vivo stability while preserving receptor recognition.

Areas of scientific investigation

  • Protease-resistant GHRH analog chemistry
  • Visceral adipose tissue models
  • GH/IGF-1 axis endocrinology
  • Lipid metabolism research

Listed fields describe where this sequence appears in published in vitro and preclinical literature. They are not indications, applications, or claims of effect.

Laboratory handling

Reconstitution

Allow the vial to reach room temperature before opening to prevent condensation on the lyophilized cake. Add sterile or bacteriostatic water slowly down the inner wall of the vial, then let the powder dissolve without agitation; swirl gently if needed. Do not shake or vortex — shear forces denature peptide secondary structure and cause foaming that traps material on the stopper.

Stability

As a sealed lyophilized powder the material is stable for extended periods at -20 °C when kept desiccated and protected from light. Once in solution, stability shortens considerably: aqueous stocks are normally held at 2-8 °C for short term work or aliquoted and frozen for longer storage. Repeated freeze-thaw cycling is the most common cause of measurable potency loss.

Packaging

Single sequence per vial, sealed under inert gas in USP Type I borosilicate glass with a butyl rubber stopper and crimped aluminium overseal. Each vial carries a printed PrimeGen label with product name, strength, lot number, manufacture and retest dates, storage temperature and a QR code linking to the lot record. Vials ship in a rigid foam insert inside a protective mailer at ambient temperature.

Research use only

For laboratory research purposes only. Not intended for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. Purchasers are responsible for complying with all applicable laws and regulations.

Growth hormone releasing factor analogs and assay design

Tesamorelin is a stabilised analog of growth hormone releasing hormone, and the modification that defines it — a trans-3-hexenoyl group on the N-terminus — exists to blunt dipeptidyl peptidase-4 cleavage at the second residue. In practical terms that means the sequence tolerates the incubation times used in pituitary-cell and receptor-binding work far better than native GHRH, which is why it appears so often as a comparator in secretagogue literature rather than as a novelty.

Assays built around GHRH-receptor pharmacology read cAMP accumulation, so the usual confounders apply: serum protein in the medium, adsorption of peptide to untreated polypropylene at low concentrations, and freeze-thaw cycling of the working stock. Low-bind tubes and single-use aliquots remove most of the variance that laboratories otherwise attribute to the material.

Comparative work frequently pairs a releasing-factor analog with a ghrelin-receptor secretagogue to separate the two arms of growth-hormone regulation. The library article on growth hormone secretagogues sets out how that distinction is drawn in the published literature.

The 20 mg Tesamorelin presentation

This page documents one specific presentation: a sealed vial filled to a nominal 20 mg of lyophilized Tesamorelin, released at 99.0% chromatographic purity by reverse-phase HPLC and confirmed for identity by an independent laboratory. Each fill weight is catalogued separately because each has its own lot history and its own certificate of analysis — the analytical summary shown here belongs to this presentation rather than to the compound in general.

At $132.00 per vial the 20 mg presentation works out at roughly $6.60 per nominal milligram of peptide before any volume discount. That figure is the only fair basis for comparing this listing with another supplier's, since vial price alone says nothing about how much material is inside. Note that it is calculated on nominal fill weight; net peptide content on the lot certificate is lower, because lyophilized peptide also carries counter-ion and residual moisture.

Tesamorelin is also catalogued as 2 mg, 5 mg, 10 mg. Choosing between them is a planning decision rather than a pricing one: the controlling factor is how much material a study can consume once a vial is opened and reconstituted, because a sealed dry vial is stable for a long period while a working solution is not. Buying a larger fill to lower the unit cost and then discarding half of it after repeated freeze-thaw cycling introduces exactly the variability the experiment is trying to avoid.

  • Nominal fill: 20 mg of lyophilized powder in a sealed USP Type I borosilicate vial.
  • Released purity: 99.0% by RP-HPLC, with identity confirmed by third-party HPLC and mass spectrometry.
  • Published average molecular weight: 5135.9 g/mol.
  • Supplied without diluent — the receiving laboratory selects diluent, concentration and aliquoting strategy.
  • Certificates are issued digitally against the lot code and are not enclosed in the shipment.

Tesamorelin 20 mg — laboratory research dossier

This dossier collects everything a laboratory typically needs before requisitioning Tesamorelin at the 20 mg presentation: how the sequence is characterised in published literature, how the material is assayed and released, how it should be stored and reconstituted, and where it sits inside the wider growth hormone research catalogue. Every unit is supplied as a sealed lyophilized powder at 99.0% and is sold exclusively for laboratory research use. It is not a drug, dietary supplement or cosmetic, and it is not intended for human or veterinary use.

Scientific background

Tesamorelin is a GHRH(1-44) analog bearing a trans-3-hexenoyl group on the N-terminal tyrosine. The acylation is the defining structural feature and the reason it appears in literature concerned with protease-resistant GHRH scaffolds.

Trans-3-hexenoyl GHRH analog referenced in visceral adipose-tissue research. Investigators most often encounter this sequence in protease-resistant ghrh analog chemistry and in visceral adipose tissue models, which is why the 20 mg vial is the format we release most frequently — it gives enough material for a full dose-response series at typical assay concentrations without leaving a large reconstituted surplus to store. This compound is catalogued at 4 strengths (2 mg, 5 mg, 10 mg, 20 mg), so a study can be scaled without changing lot chemistry.

Mechanism of action in published work

Binds and activates the GHRH receptor with potency comparable to native hormone. The hexenoyl modification blocks N-terminal DPP-4 attack, extending in vitro and in vivo stability while preserving receptor recognition.

Descriptions above summarise observations reported in peer reviewed in vitro and animal literature. They describe what has been measured in model systems and are not claims of effect, indications, or guidance for use in humans or animals. Laboratories designing new work should return to the primary literature for concentration ranges, vehicle selection and control design, because reported effects in this class are strongly assay dependent.

Research applications

Published work involving Tesamorelin clusters into a small number of recurring experimental settings:

  • Protease-resistant GHRH analog chemistry
  • Visceral adipose tissue models
  • GH/IGF-1 axis endocrinology
  • Lipid metabolism research

Because these are in vitro and preclinical contexts, the practical requirement on the material itself is consistency: a known mass of a single sequence, a stated purity, and a lot record that can be cited in a methods section. That is what the 20 mg vial and its accompanying certificate of analysis are designed to provide.

Analytical identity and specification

Compound
Tesamorelin
Presentation
20 mg lyophilized powder, single sequence per vial
Reported purity
99.0% by RP-HPLC
Molecular formula
C221H366N72O67S
Molecular weight
5135.9 g/mol
CAS number
218949-48-5
Appearance
White to off-white lyophilized powder or cake, free of visible particulates.
Unit price
$132.00 per vial

Purity, quality control and the certificate of analysis

Each Tesamorelin lot is assayed in house by reverse-phase HPLC and then re-tested by an independent analytical laboratory using HPLC alongside mass spectrometry for identity confirmation. The HPLC trace establishes the chromatographic purity figure printed on the label — 99.0% for the current release — while the mass spectrometry step confirms that the observed molecular ion matches the expected mass for the sequence rather than a truncated or deletion analogue.

Certificates are issued digitally rather than enclosed in the shipment, which keeps the document versioned and retrievable long after the vial is consumed. You can view or request the current report from the certificates library, and the underlying chromatograms and spectra can be requested through laboratory support. Our full release criteria are documented on the quality control and laboratory standards pages.

Storage, reconstitution and stability

Storage. Sealed 20 mg vials are held desiccated and protected from light. Short holding periods at 2-8 °C are routine; for longer storage the lyophilized cake is kept at -20 °C. Allow the vial to equilibrate to room temperature before breaking the seal so that atmospheric moisture does not condense onto the powder.

Reconstitution. Allow the vial to reach room temperature before opening to prevent condensation on the lyophilized cake. Add sterile or bacteriostatic water slowly down the inner wall of the vial, then let the powder dissolve without agitation; swirl gently if needed. Do not shake or vortex — shear forces denature peptide secondary structure and cause foaming that traps material on the stopper.

Stability. As a sealed lyophilized powder the material is stable for extended periods at -20 °C when kept desiccated and protected from light. Once in solution, stability shortens considerably: aqueous stocks are normally held at 2-8 °C for short term work or aliquoted and frozen for longer storage. Repeated freeze-thaw cycling is the most common cause of measurable potency loss.

Handling. Work with the reconstituted solution under standard laboratory containment, record the reconstitution volume and date against the lot, and label aliquots with the resulting concentration. Volumes and concentrations are set by your own protocol; nothing on this page is a dosing instruction.

Experimental design considerations

The most common source of irreproducibility with lyophilized peptides is not the sequence itself but the arithmetic around it. A 20 mg vial contains a nominal peptide mass; the actual peptide content of any lyophilized cake also reflects counter-ion and residual moisture content, so laboratories reporting exact molar concentrations should either use the net peptide content figure from the lot certificate or determine content independently by amino acid analysis or quantitative UV. Using the published average mass of 5135.9 g/mol, a full 20 mg vial reconstituted in 1 mL of diluent gives a convenient round stock concentration for serial dilution.

Three practical points recur in method sections for this class of material:

  • Vehicle matters. Record the diluent, its preservative content and its pH alongside the concentration. Bacteriostatic and sterile water are not interchangeable in every assay, and benzyl alcohol can interfere with sensitive cell based readouts.
  • Adsorption is real. At low working concentrations, peptides adsorb to polypropylene and glass. Low-bind labware or a carrier protein in the dilution buffer keeps the delivered concentration close to the nominal one.
  • Cite the lot. Because purity, counter-ion and net content vary between syntheses, methods sections should name the supplier lot for Tesamorelin so a later replication can be matched to the same analytical record.

Where a study spans several weeks, aliquoting the reconstituted stock immediately and freezing single-use volumes avoids the freeze-thaw cycling that accounts for most of the potency drift observed in longitudinal work.

Choosing the right presentation

Tesamorelin is released at 2 mg, 5 mg, 10 mg, 20 mg. Larger presentations lower the cost per milligram but commit a laboratory to using or storing more reconstituted material; smaller vials suit pilot work, method development and screening plates where a single stock is consumed quickly. The 20 mg vial listed on this page is priced at $132.00. Whatever presentation you select, the underlying material comes from the same synthesis and release programme, so switching strength does not change the analytical profile.

Orders ship from our facility in Chase City, Virginia, within the United States only, and every shipment carries the research use restriction on the outer documentation. Vials travel at ambient temperature in a rigid insert; lyophilized peptide is stable for the transit window, and the material should be moved to its long term storage temperature on arrival. Research materials are non returnable once dispatched.

Related research compounds and documentation

Laboratories sourcing Tesamorelin frequently reference Semaglutide 2 mg, Tirzepatide 5 mg, Retatrutide 5 mg and Cagrilintide 5 mg alongside it, either as comparators in the same assay or as adjacent sequences in the same pathway literature.

This compound is catalogued under Research Peptides, Weight Management Research, Growth Hormone Research. The complete research compound catalogue lists every sequence and strength we hold.

Background reading in the research library: Growth hormone secretagogues: GHRH analogs versus ghrelin mimetics, What are research peptides?, Understanding lyophilized powders.

Ordering details, transit times and our US shipping guarantee are set out on the shipping policy page, and general purchasing and compliance questions are answered in the frequently asked questions. Terms of sale, including our no returns policy on research materials, are published on the terms page.

Quality programme and laboratory support

Every Tesamorelin release passes through the same programme: synthesis against a defined sequence, in-house RP-HPLC purity assay, independent third party HPLC and mass spectrometry confirmation, visual inspection of the lyophilized cake, and a documented fill and seal step under inert gas in USP Type I borosilicate glass. Material that fails any stage is not released, and the certificate published for a lot is the certificate generated for that specific synthesis — never a representative or historical document carried over from an earlier batch.

Laboratories evaluating Tesamorelin for the first time frequently ask for the raw analytical files rather than the summary certificate. Chromatograms, mass spectra and, where applicable, net peptide content data can be requested for any lot; our support team answers analytical questions directly rather than through a ticket queue. Institutional purchasing, repeat supply for multi-month studies and quotations for multiple strengths are handled the same way.

Terminology used on this page

Lyophilized
Freeze dried under vacuum. Removing water as vapour rather than liquid leaves a porous cake that dissolves quickly and is far more stable in storage than a peptide held in solution, which is why Tesamorelin is supplied this way rather than pre-reconstituted.
RP-HPLC purity
Reverse-phase high performance liquid chromatography separates the target sequence from synthesis-related impurities by hydrophobicity. The reported figure — 99.0% for this material — is the target peak area as a percentage of total integrated peak area.
Mass spectrometry confirmation
An orthogonal identity check. Purity alone cannot distinguish the correct sequence from a co-eluting analogue of similar hydrophobicity; measuring the molecular ion against the expected 5135.9 g/mol confirms that the peak being integrated is the intended molecule.
Net peptide content
The fraction of the vial mass that is peptide rather than counter-ion or residual water. It is the figure to use when converting a 20 mg fill into an exact molar stock concentration.
Research use only
The material is sold for in vitro and laboratory investigation by qualified personnel. It is not a medicine, supplement, food or cosmetic, carries no approval for human or veterinary administration, and must be handled under the purchasing institution’s own safety procedures.

Literature and further reading

The characterisations summarised above are drawn from peer reviewed in vitro and preclinical publications indexed in PubMed and from the corresponding entries in ChEMBL, PubChem and UniProt. Searching the compound name “Tesamorelin or CAS 218949-48-5 in those databases returns the primary sources for the mechanism and application notes on this page. PrimeGen Co. does not publish clinical data and makes no therapeutic claim for this or any other catalogue item.

For laboratory research use only. Not for human or veterinary use. Not a drug, supplement, food or cosmetic. Read our research use policy before ordering.

Frequently asked questions

What is included with each Tesamorelin vial?

Each unit contains 20 mg of lyophilized Tesamorelin in a sealed vial. The lot matched certificate of analysis is available digitally on the Certificates page and is not physically enclosed in the shipment.

How is purity verified?

Every lot is assayed in house by RP-HPLC and then re-tested by an independent laboratory using HPLC and mass spectrometry. This lot reports 99.0%.

How should the vial be reconstituted?

Reconstitution parameters depend on your protocol. Use bacteriostatic or sterile diluent, add slowly against the vial wall, and swirl rather than shake to avoid shearing the peptide.

Can I request the raw analytical data?

Yes. Chromatograms and MS spectra for any lot can be requested through the certificates page or by contacting the laboratory support team.

Is Tesamorelin intended for human use?

No. Tesamorelin is supplied strictly as a laboratory research chemical. It is not a drug, dietary supplement, or cosmetic, it is not approved for human or veterinary use, and it must not be administered to humans or animals.

How should Tesamorelin be stored before and after reconstitution?

Sealed 20 mg vials are held desiccated, protected from light, and away from repeated temperature swings; 2-8 °C suits short holding periods while -20 °C is used for longer storage of the lyophilized cake. Once reconstituted, the solution is normally kept at 2-8 °C for near-term work or aliquoted into single-use volumes and frozen, since repeated freeze-thaw cycling is the most common cause of measurable potency loss.

How much material is in one Tesamorelin vial?

Each vial is filled to a nominal 20 mg of lyophilized peptide, with a published average molecular weight of 5135.9 g/mol. Because lyophilized peptide also carries counter-ion and residual moisture, laboratories reporting exact molar concentrations should use the net peptide content on the lot certificate or determine content independently.

What analytical methods are used to release a Tesamorelin lot?

Every lot is assayed in house by reverse-phase HPLC for chromatographic purity, then re-tested by an independent laboratory using HPLC alongside mass spectrometry to confirm that the observed mass matches the expected sequence rather than a truncated or deletion analogue. The release specification is ≥ 98% by RP-HPLC; this lot reports 99.0%.

Does Tesamorelin ship internationally?

No. Orders ship within the United States only, dispatched directly from our facility in Chase City, Virginia. Vials travel at ambient temperature in a rigid protective insert, and the lyophilized powder is stable across the transit window; move the material to its long-term storage temperature on arrival.

Can Tesamorelin be returned or exchanged?

No. Research materials are non-returnable once dispatched, because chain-of-custody and storage conditions cannot be verified after a vial leaves the facility. If a shipment arrives damaged or a lot does not match its certificate of analysis, contact laboratory support and we will resolve it directly.

Compare with similar compounds

Tesamorelin vs CJC-1295 DAC, CJC-1295 No DAC, Sermorelin

Open full comparison
Tesamorelin compared with similar research compounds
CompoundStrengthCategoryMolecular weightAvailabilityPrice
TesamorelinThis page20 mgGrowth Hormone Research5135.9 g/molIn stock$132.00
CJC-1295 DAC2 mgGrowth Hormone Research3647.2 g/molLow stock · few lots left$20.00
CJC-1295 No DAC2 mgGrowth Hormone Research3367.9 g/molIn stock$16.00
Sermorelin5 mgGrowth Hormone Research3357.9 g/molIn stock$27.00

Complete your order

Laboratory consumables matched to 1 vial in your cart.

  • Bacteriostatic Water, 30 mL, laboratory consumable supplied by PrimeGen Co.

    Bacteriostatic Water

    30 mL

    1 × 30 mL — one vial of diluent per 3 peptide vials

    $16.00
  • Sterile Syringes, 10-pack · 1 mL, laboratory consumable supplied by PrimeGen Co.

    Sterile Syringes

    10-pack · 1 mL

    10-pack covers a standard order

    $13.00
  • Alcohol Prep Pads, 100-pack, laboratory consumable supplied by PrimeGen Co.

    Alcohol Prep Pads

    100-pack

    Septum decontamination before every draw

    $9.00
  • Vial Storage Case, 25 slots, laboratory consumable supplied by PrimeGen Co.

    Vial Storage Case

    25 slots

    Keeps lots organised and light-protected

    $33.00

Researchers also viewed

Alternative compounds

Other compounds catalogued alongside Tesamorelin in Growth Hormone Research. All items are supplied for laboratory research use only.

View Growth Hormone Research

Explore further

Continue from Tesamorelin into compounds studied alongside it, the kits that include it, the analytical documentation behind this lot, and the library articles covering its category.

Tesamorelin · 20 mg

In stock

$132.00